It's more on the cellular receptors. From AI google: "Nicotinic acetylcholine receptors (nAChRs) are receptor polypeptides that respond to nicotine, the addictive component of tobacco smoke, and the neurotransmitter acetylcholine. They are found in the central and peripheral nervous systems, muscle, and many other tissues of many organisms.
Nicotine acts as an agonist and a desensitizing agent on nAChRs. When nicotine binds to nAChRs in the brain, it increases the release of many neurotransmitters, including dopamine, serotonin, norepinephrine, acetylcholine, gamma-aminobutyric acid, and glutamate. This can produce an important difference in brain activity between smokers and non-smokers."
ACE2 receptors ?
It's more on the cellular receptors. From AI google: "Nicotinic acetylcholine receptors (nAChRs) are receptor polypeptides that respond to nicotine, the addictive component of tobacco smoke, and the neurotransmitter acetylcholine. They are found in the central and peripheral nervous systems, muscle, and many other tissues of many organisms.
Nicotine acts as an agonist and a desensitizing agent on nAChRs. When nicotine binds to nAChRs in the brain, it increases the release of many neurotransmitters, including dopamine, serotonin, norepinephrine, acetylcholine, gamma-aminobutyric acid, and glutamate. This can produce an important difference in brain activity between smokers and non-smokers."
Dr. Ardis stated that nicotine is not addictive. He said the cigarette companies add a chemical to the nicotine to make it addictive.
nicotine patches are not addictive.
Yes, that is what I am saying.